Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 18/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 18/20 | 0.49 |
| ▸ | GRN | P28799 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403313 | 0.86 | GAA (0.48) | TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL6434625 | 0.84 | NPSR1 (0.48) | TAS1R3TAS1R1GRNSORT1CA1 | |
| SCHEMBL6434626 | 0.84 | NPSR1 (0.48) | TAS1R3TAS1R1GRNSORT1CA1 | |
| SCHEMBL7403061 | 0.80 | HPGD (0.43) | TAS1R3TAS1R1 | |
| SCHEMBL7406871 | 0.79 | POLB (0.52) | — | |
| SCHEMBL28814272 | 0.74 | TAS1R3 (0.60) | TAS1R3TAS1R1 | |
| SCHEMBL7390699 | 0.74 | GAA (0.44) | CA1CA2 | |
| SCHEMBL6435509 | 0.74 | GRN (0.38) | TAS1R3TAS1R1GRNSORT1 | |
| SCHEMBL7367854 | 0.73 | PPARG (0.42) | TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL7401270 | 0.73 | CA2 (0.55) | GRNSORT1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |