Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 14/20 | 0.88 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.88 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL737074 | 1.00 | GHSR (0.88) | GHSROPRM1ACEKDM4EMEN1 | |
| Macimorelin SCHEMBL1984708 | 0.94 | GHSR (1.00) | GHSROPRM1ACEALOX15 | |
| Macimorelin SCHEMBL1743598 | 0.94 | GHSR (1.00) | GHSROPRM1ACEALOX15 | |
| Macimorelin SCHEMBL15533638 | 0.94 | GHSR (1.00) | GHSROPRM1ACEALOX15 | |
| Macimorelin SCHEMBL29359318 | 0.91 | GHSR (0.94) | GHSROPRM1ACEALOX15 | |
| SCHEMBL736941 | 0.91 | GHSR (0.71) | GHSROPRM1ACE | |
| SCHEMBL737877 | 0.87 | GHSR (0.81) | GHSROPRM1ACE | |
| SCHEMBL737619 | 0.87 | GHSR (0.81) | GHSROPRM1ACEECE1 | |
| SCHEMBL737019 | 0.86 | GHSR (0.85) | GHSROPRM1ACEALOX15 | |
| SCHEMBL736951 | 0.86 | GHSR (0.85) | GHSROPRM1ACEALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138218-B2 | Growth hormone secretagogues | IPSEN PHARMA S.A.S. (FR) | 2012-03-20 | — | — | US | disclosed |
| US-20090131478-A1 | Growth Hormone Secretagogues | IPSEN PHARMA S.A.S. (FR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131478-A1 | Growth Hormone Secretagogues | GHSR, GHRHR, GHITM | GHSR 1/4885OPRM1 3398/4885ACE 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.