Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5064235 | 0.84 | CCR1 (0.58) | CCR1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL7374208 | 0.83 | MEN1 (0.47) | KDM4EMEN1KMT2AMAPK1TP53 | |
| SCHEMBL7370205 | 0.82 | CCR1 (0.56) | CCR1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL7373471 | 0.81 | ALDH1A1 (0.55) | KDM4EMEN1KMT2AMAPK1TP53 | |
| SCHEMBL5064434 | 0.81 | KDM4E (0.58) | CCR1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL5061535 | 0.80 | CCR1 (0.56) | CCR1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL5066421 | 0.80 | CCR1 (0.58) | CCR1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL5060462 | 0.80 | CCR1 (0.63) | CCR1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL5064014 | 0.79 | ALDH1A1 (0.60) | CCR1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL5060360 | 0.79 | MRGPRX4 (0.56) | CCR1KDM4EMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929074-A | VSODILATOR, ANTIALLERGIC AND ANTIPLATELET AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0706517-B1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL IND LTD (JP) | 1998-10-21 | — | — | EP | disclosed |
| US-5728702-A | BRONCHODILATOR AGENTS, ANTIALLERGENS OR ANTIPLATELET DRUGGS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0706517-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001343-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |