Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | RABGGTB | P53611 | 1/20 | 0.31 |
| ▸ | RABGGTA | Q92696 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368916 | 1.00 | ADORA2A (0.35) | ADORA2AADORA2BGPR119MEN1KMT2A | |
| SCHEMBL7368920 | 1.00 | ADORA2A (0.35) | ADORA2AADORA2BGPR119MEN1KMT2A | |
| SCHEMBL7375102 | 0.95 | ADORA2A (0.34) | ADORA2AADORA2BGPR119MEN1KMT2A | |
| SCHEMBL7375103 | 0.95 | ADORA2A (0.34) | ADORA2AADORA2BGPR119MEN1KMT2A | |
| SCHEMBL7375107 | 0.95 | ADORA2A (0.34) | ADORA2AADORA2BGPR119MEN1KMT2A | |
| SCHEMBL7372865 | 0.90 | ADORA2B (0.36) | ADORA2AADORA2BGPR119MEN1KMT2A | |
| SCHEMBL7372868 | 0.90 | ADORA2B (0.36) | ADORA2AADORA2BGPR119MEN1KMT2A | |
| SCHEMBL7372869 | 0.90 | ADORA2B (0.36) | ADORA2AADORA2BGPR119MEN1KMT2A | |
| SCHEMBL7369150 | 0.89 | BMP1 (0.36) | ADORA2AADORA2BGPR119MEN1KMT2A | |
| SCHEMBL7369015 | 0.89 | BMP1 (0.36) | ADORA2AADORA2BGPR119MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310015-A2 | Renin-inhibiting dipeptides, process for their preparation, medicines containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-05 | — | — | EP | disclosed |