Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367965 | 0.88 | ADRB3 (0.60) | KMT2AMEN1ADRB3ADRB1ADRB2 | |
| SCHEMBL7369310 | 0.86 | KDM4E (0.62) | CASRKMT2AMAPK1ADRB3ADRB1 | |
| SCHEMBL7364771 | 0.85 | MEN1 (0.62) | KMT2AMEN1MAPTSMN1; SMN2ADRB3 | |
| SCHEMBL7367538 | 0.85 | MEN1 (0.62) | KMT2AMEN1MAPTSMN1; SMN2ADRB3 | |
| SCHEMBL7367855 | 0.84 | MEN1 (0.63) | KMT2AMEN1MAPTSMN1; SMN2ADRB3 | |
| SCHEMBL6690111 | 0.80 | MEN1 (0.65) | KMT2AMEN1MAPTSMN1; SMN2ADRB3 | |
| SCHEMBL11616553 | 0.78 | CASR (0.49) | CASRKMT2AMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18506356 | 0.76 | KDM4E (0.56) | KMT2AMEN1TAAR1MAPK1ADRB3 | |
| SCHEMBL8778541 | 0.75 | HRH3 (0.57) | KMT2AMEN1MAPK1SMN1; SMN2DRD2 | |
| SCHEMBL28540629 | 0.75 | HRH3 (0.57) | KMT2AMEN1MAPK1SMN1; SMN2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002463-A1 | ANTIHYPERTENSIVE 1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-03 | — | — | WO | disclosed |