Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540629 | 1.00 | HRH3 (0.57) | HRH3DRD2DRD4LMNAMAPK1 | |
| SCHEMBL6470787 | 0.93 | DRD2 (0.58) | HRH3DRD2DRD4LMNAMAPK1 | |
| SCHEMBL2000837 | 0.87 | LMNA (0.59) | HRH3DRD2DRD4LMNAMAPK1 | |
| SCHEMBL9774806 | 0.83 | DRD2 (0.60) | HRH3DRD2DRD4LMNAMAPK1 | |
| SCHEMBL9808215 | 0.82 | LMNA (0.67) | HRH3DRD2DRD4LMNAMAPK1 | |
| SCHEMBL8955728 | 0.82 | HRH3 (0.57) | HRH3DRD2DRD4LMNAMAPK1 | |
| SCHEMBL8035908 | 0.82 | HRH3 (0.57) | HRH3DRD2DRD4LMNAMAPK1 | |
| SCHEMBL10632624 | 0.82 | HRH3 (0.57) | HRH3DRD2DRD4LMNAMAPK1 | |
| SCHEMBL1685432 | 0.81 | DRD2 (0.62) | HRH3DRD2DRD4LMNAMAPK1 | |
| SCHEMBL6846964 | 0.80 | DRD2 (0.57) | HRH3DRD2DRD4LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |