Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.61 |
| ▸ | FAP | Q12884 | 3/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.53 |
| ▸ | AKT1 | P31749 | 4/20 | 0.52 |
| ▸ | AKT2 | P31751 | 1/20 | 0.52 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.52 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | AKT1S1 | Q96B36 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367542 | 0.90 | DPP4 (0.51) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL7360569 | 0.90 | HDAC8 (0.55) | DPP4HRH2HRH1OPRK1 | |
| SCHEMBL7361667 | 0.88 | OPRK1 (0.57) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL7360354 | 0.85 | F2 (0.49) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL7364169 | 0.85 | DPP4 (0.55) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL2606773 | 0.85 | DPP4 (0.62) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL2606751 | 0.85 | DPP4 (0.62) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL4327505 | 0.85 | DPP4 (0.62) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL3140707 | 0.85 | DPP4 (0.65) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL3145720 | 0.85 | DPP4 (0.65) | DPP4FAPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |