Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.57 |
| ▸ | DPP4 | P27487 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.51 |
| ▸ | FAP | Q12884 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | AKT2 | P31751 | 1/20 | 0.51 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5366189 | 0.89 | HDAC8 (0.59) | OPRK1HDAC8OPRD1DPP4POLB | |
| SCHEMBL7368941 | 0.88 | DPP4 (0.61) | OPRK1DPP4DPP8DPP9DPP7 | |
| SCHEMBL7367542 | 0.88 | DPP4 (0.51) | OPRK1OPRD1DPP4DPP8DPP9 | |
| SCHEMBL7364618 | 0.88 | OPRK1 (0.57) | OPRK1HDAC8OPRD1DPP4POLB | |
| SCHEMBL7360569 | 0.88 | HDAC8 (0.55) | OPRK1HDAC8OPRD1DPP4SMYD3 | |
| SCHEMBL2375481 | 0.86 | OPRK1 (0.71) | OPRK1HDAC8OPRD1DPP4POLB | |
| SCHEMBL2375476 | 0.86 | OPRK1 (0.71) | OPRK1HDAC8OPRD1DPP4POLB | |
| Hydrochloric Acid SCHEMBL7370444 | 0.86 | OPRD1 (0.52) | OPRK1HDAC8OPRD1DPP4POLB | |
| Hydrochloric Acid SCHEMBL7370442 | 0.86 | OPRD1 (0.52) | OPRK1HDAC8OPRD1DPP4POLB | |
| SCHEMBL7360354 | 0.84 | F2 (0.49) | OPRK1OPRD1DPP4POLBDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |