Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360627 | 0.94 | MAPT (0.54) | MAPTSMN1; SMN2LMNAALDH1A1L3MBTL1 | |
| SCHEMBL22911172 | 0.93 | MAPT (0.58) | MAPTSMN1; SMN2LMNAALDH1A1L3MBTL1 | |
| SCHEMBL7359036 | 0.89 | MAPT (0.49) | MAPTSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL12814098 | 0.88 | NPSR1 (0.55) | MAPTSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL7358222 | 0.87 | GPR119 (0.51) | MAPTSMN1; SMN2LMNAALDH1A1GPR119 | |
| SCHEMBL7360159 | 0.86 | GPR119 (0.53) | MAPTSMN1; SMN2LMNAALDH1A1GPR119 | |
| SCHEMBL7365688 | 0.86 | GPR119 (0.53) | MAPTSMN1; SMN2LMNAALDH1A1GPR119 | |
| SCHEMBL7366689 | 0.86 | GPR119 (0.47) | MAPTSMN1; SMN2LMNAALDH1A1GPR119 | |
| SCHEMBL31716461 | 0.85 | MAPT (0.54) | MAPTSMN1; SMN2LMNAALDH1A1L3MBTL1 | |
| SCHEMBL24378197 | 0.85 | MAPT (0.61) | MAPTSMN1; SMN2LMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |