Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477714 | 0.90 | GPR119 (0.54) | GPR119MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8477717 | 0.90 | GPR119 (0.48) | GPR119MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7369010 | 0.86 | MAPT (0.59) | GPR119MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7365688 | 0.86 | GPR119 (0.53) | GPR119MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8478702 | 0.85 | GPR119 (0.51) | GPR119MAPTLMNASMN1; SMN2 | |
| SCHEMBL7369003 | 0.83 | GPR119 (0.50) | GPR119MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7364852 | 0.83 | GPR119 (0.51) | GPR119MAPT | |
| SCHEMBL8474377 | 0.83 | GPR119 (0.50) | GPR119MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8477312 | 0.83 | GPR119 (0.48) | GPR119 | |
| SCHEMBL7359036 | 0.82 | MAPT (0.49) | GPR119MAPTLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |