Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Name SCHEMBL29362113 | 0.85 | NOS1 (0.41) | F2NOS1ADAM17DDAH1TSHR | |
| L-Name SCHEMBL5966636 | 0.85 | NOS1 (0.41) | F2NOS1ADAM17DDAH1TSHR | |
| Hydrochloric Acid SCHEMBL7365158 | 0.84 | DDAH1 (0.38) | F2NOS1ADAM17DDAH1 | |
| L-Name SCHEMBL6054203 | 0.81 | NOS1 (0.38) | F2NOS1ADAM17DDAH1TSHR | |
| SCHEMBL8376062 | 0.79 | MEN1 (0.38) | F2 | |
| SCHEMBL13084706 | 0.78 | NOS1 (0.36) | F2NOS1ADAM17DDAH1 | |
| SCHEMBL12237928 | 0.78 | NOS1 (0.36) | F2NOS1ADAM17DDAH1 | |
| SCHEMBL14350781 | 0.76 | NOS1 (0.40) | F2NOS1ADAM17DDAH1 | |
| SCHEMBL12556165 | 0.76 | MEN1 (0.39) | F2NOS1ADAM17DDAH1LTA4H | |
| SCHEMBL12556286 | 0.76 | MEN1 (0.39) | F2NOS1ADAM17DDAH1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664786-B1 | ARGININE KETO-AMIDE ENZYME INHIBITORS | CORVAS INT INC (US) | 1999-03-24 | — | — | EP | disclosed |
| US-5869454-A | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. (US) | 1999-02-09 | — | — | US | disclosed |
| US-5670479-A | α-ketoamide derivatives as inhibitors of thrombosis | CORVAS INTERNATIONAL, INC. (US) | 1997-09-23 | — | — | US | disclosed |
| US-5656600-A | MODIFIED POLYPEPTIDES | CORVAS INTERNATIONAL, INC. (US) | 1997-08-12 | — | — | US | disclosed |
| US-5597804-A | ANTITHROMBOTIC AGENTS | CORVAS INTERNATIONAL, INC. (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0693083-A4 | ALPHA-KETOAMIDE DERIVATIVES AS INHIBITORS OF THROMBOSIS | CORVAS INT INC (US) | 1996-07-17 | — | — | EP | disclosed |
| EP-0693083-A1 | ALPHA-KETOAMIDE DERIVATIVES AS INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1996-01-24 | — | — | EP | disclosed |
| US-5371072-A | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. (US) | 1994-12-06 | — | — | US | disclosed |
| WO-1994021673-A1 | ALPHA-KETOAMIDE DERIVATIVES AS INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1994-09-29 | — | — | WO | disclosed |