Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28404629 | 0.89 | ALDH1A1 (0.60) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL5988339 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL14504458 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL18256779 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL7602589 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL7604426 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL7369373 | 0.79 | ALOX15 (0.50) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL10345378 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL1469974 | 0.78 | ALDH1A1 (0.52) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL1469220 | 0.78 | ALDH1A1 (0.52) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242600-B1 | ANTIISCHEMIC AGENTS, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0970071-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039324-A1 | 2-PEPERAZINONE-1-ACETIC ACID DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-11 | — | — | WO | disclosed |