Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.30 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697839 | 0.84 | GHSR (0.47) | GHSR | |
| Hydrochloric Acid SCHEMBL7371113 | 0.83 | GHSR (0.35) | GHSR | |
| SCHEMBL7370845 | 0.80 | GHSR (0.37) | GHSR | |
| SCHEMBL7371725 | 0.74 | GHSR (0.43) | GHSR | |
| SCHEMBL7868472 | 0.72 | GHSR (0.40) | GHSRMAPK11MAPK14 | |
| SCHEMBL5013587 | 0.64 | GHSR (0.70) | GHSR | |
| SCHEMBL5013586 | 0.64 | GHSR (0.70) | GHSR | |
| Hydrochloric Acid SCHEMBL7489609 | 0.63 | GHSR (0.69) | GHSR | |
| Hydrochloric Acid SCHEMBL7489605 | 0.63 | GHSR (0.69) | GHSR | |
| Hydrochloric Acid SCHEMBL9391073 | 0.61 | GHSR (0.48) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994013696-A1 | SPIRO PIPERIDINES AND HOMOLOGS WHICH PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | claimed |