Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495162 | 0.89 | GHSR (0.44) | GHSR | |
| SCHEMBL7918487 | 0.88 | GHSR (0.43) | GHSR | |
| Hydrochloric Acid SCHEMBL8590141 | 0.84 | GHSR (0.38) | GHSR | |
| SCHEMBL8150673 | 0.83 | GHSR (0.57) | GHSR | |
| SCHEMBL7759453 | 0.76 | GHSR (0.51) | GHSR | |
| SCHEMBL5013587 | 0.74 | GHSR (0.70) | GHSR | |
| SCHEMBL5013586 | 0.74 | GHSR (0.70) | GHSR | |
| Hydrochloric Acid SCHEMBL7489605 | 0.73 | GHSR (0.69) | GHSR | |
| Hydrochloric Acid SCHEMBL7489609 | 0.73 | GHSR (0.69) | GHSR | |
| SCHEMBL7369459 | 0.72 | GHSR (0.33) | GHSRMAPK14MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071423-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 2001-01-31 | — | — | EP | disclosed |
| EP-0986550-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 2000-03-22 | — | — | EP | disclosed |
| WO-1999051234-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1999-10-14 | — | — | WO | disclosed |
| WO-1998055470-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1998-12-10 | — | — | WO | disclosed |