Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1137942 | 0.84 | GABRA1 (0.46) | GABRA1GABRB2TSHRFOLH1ALDH1A1 | |
| SCHEMBL2731264 | 0.84 | MRGPRX4 (0.46) | MRGPRX4TSHRFOLH1ALDH1A1POLB | |
| SCHEMBL89060 | 0.83 | FOLH1 (0.55) | GABRA1GABRB2TSHRFOLH1ALDH1A1 | |
| Benzene SCHEMBL27083018 | 0.83 | FOLH1 (0.55) | GABRA1GABRB2TSHRFOLH1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL16531812 | 0.82 | FOLH1 (0.53) | GABRA1GABRB2TSHRFOLH1ALDH1A1 | |
| Phosphine SCHEMBL28264956 | 0.82 | FOLH1 (0.53) | GABRA1GABRB2TSHRFOLH1ALDH1A1 | |
| SCHEMBL11094883 | 0.82 | FOLH1 (0.53) | GABRA1GABRB2TSHRFOLH1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7974299 | 0.82 | FOLH1 (0.53) | GABRA1GABRB2TSHRFOLH1ALDH1A1 | |
| Potassium SCHEMBL16531822 | 0.82 | FOLH1 (0.53) | GABRA1GABRB2TSHRFOLH1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL9940062 | 0.82 | FOLH1 (0.53) | GABRA1GABRB2TSHRFOLH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409538-A | Allyl benzoate compound and preparation method thereof | 湖北工业大学 | 2022-04-29 | — | — | CN | claimed |
| EP-0695184-B1 | HIV PROTEASE INHIBITORS | AGOURON PHARMA (US) | 1999-04-21 | — | — | EP | disclosed |
| US-5863950-A | AMIDES OR THIO AMIDE COMPOUNDS WITH HYDROXY OR ETHER GROUPS | AGOURON PHARMACEUTICALS, INC. (US) | 1999-01-26 | — | — | US | disclosed |
| US-5714518-A | HIV protease inhibitors and methods of making the same | AGOURON PHARMACEUTICALS (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0695184-A4 | HIV PROTEASE INHIBITORS | AGOURON PHARMA (US) | 1996-05-22 | — | — | EP | disclosed |
| EP-0695184-A1 | HIV PROTEASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994015906-A1 | HIV PROTEASE INHIBITORS AND THEIR PREPARATION | AGOURON PHARMACEUTICALS, INC. (US) | 1994-07-21 | — | — | WO | disclosed |
| WO-1994015608-A1 | HIV PROTEASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1994-07-21 | — | — | WO | disclosed |