Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369861 | 1.00 | FAAH (0.62) | FAAHHRH3NPC1TP53RAB9A | |
| SCHEMBL3032035 | 0.88 | FAAH (0.59) | FAAHHRH3NPC1TP53RAB9A | |
| SCHEMBL3032030 | 0.88 | FAAH (0.59) | FAAHHRH3NPC1TP53RAB9A | |
| SCHEMBL1360148 | 0.88 | ALDH1A1 (0.68) | FAAHSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL1360150 | 0.88 | ALDH1A1 (0.68) | FAAHSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL7371854 | 0.87 | DPP7 (0.57) | NPC1TP53RAB9AALDH1A1MEN1 | |
| SCHEMBL7372150 | 0.87 | DPP7 (0.57) | NPC1TP53RAB9AALDH1A1MEN1 | |
| SCHEMBL7366398 | 0.87 | DPP7 (0.71) | HRH3NPC1TP53RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1361908 | 0.87 | ALDH1A1 (0.67) | FAAHSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL1361906 | 0.87 | ALDH1A1 (0.67) | FAAHSMN1; SMN2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |