Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910211 | 0.83 | SLC6A2 (0.45) | SLC6A2SIGMAR1L3MBTL1POLBMEN1 | |
| SCHEMBL11047843 | 0.78 | L3MBTL1 (0.47) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL20343995 | 0.78 | SLC6A2 (0.44) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9545400 | 0.78 | POLB (0.44) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| Butylbenzyl SCHEMBL28163480 | 0.78 | SIGMAR1 (0.55) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| Butylbenzyl SCHEMBL27286928 | 0.78 | SIGMAR1 (0.55) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| Butylbenzyl SCHEMBL27646846 | 0.78 | SIGMAR1 (0.55) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| Ethylene SCHEMBL27602640 | 0.76 | KCNH2 (0.63) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL6685035 | 0.76 | L3MBTL1 (0.48) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL1679394 | 0.76 | KCNH2 (0.48) | KCNH2CHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722436-A4 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | UNIV FLORIDA STATE (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0722436-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009833-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1995-04-13 | — | — | WO | disclosed |