Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19919908 | 0.83 | TSHR (0.55) | TSHRALDH1A1POLBBCHEACHE | |
| SCHEMBL20903627 | 0.83 | TSHR (0.55) | TSHRALDH1A1POLBBCHEACHE | |
| SCHEMBL1723877 | 0.79 | TSHR (0.51) | TSHRPOLBBCHEACHETDP1 | |
| SCHEMBL6709378 | 0.79 | TSHR (0.50) | TSHRPOLBBCHEACHETDP1 | |
| SCHEMBL10602511 | 0.77 | TSHR (0.49) | TSHRALDH1A1POLBBCHEACHE | |
| SCHEMBL6960913 | 0.76 | SMN1; SMN2 (0.64) | TSHRALDH1A1POLBBCHEACHE | |
| Hydrochloric Acid SCHEMBL7427148 | 0.75 | SMN1; SMN2 (0.62) | TSHRALDH1A1POLBBCHEACHE | |
| SCHEMBL6712789 | 0.74 | TDP1 (0.53) | TSHRALDH1A1POLBBCHEACHE | |
| SCHEMBL1769456 | 0.73 | SMN1; SMN2 (0.50) | TSHRPOLBTDP1HPGDGLA | |
| SCHEMBL1769454 | 0.73 | SMN1; SMN2 (0.50) | TSHRPOLBTDP1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028716-A1 | METHOD FOR TREATING AND PREVENTING HEART FAILURE AND VENTRICULAR DILATATION | WARNER-LAMBERT COMPANY (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1998025597-A2 | METHOD FOR TREATING AND PREVENTING HEART FAILURE AND VENTRICULAR DILATATION | WARNER-LAMBERT COMPANY (US) | 1998-06-18 | — | — | WO | disclosed |