Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.69 |
| ▸ | NPC1 | O15118 | 9/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | LMNA | P02545 | 6/20 | 0.69 |
| ▸ | PKM | P14618 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524926 | 0.87 | RAB9A (0.61) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL30708719 | 0.82 | RAB9A (1.00) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL659666 | 0.82 | RAB9A (1.00) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL659665 | 0.82 | RAB9A (1.00) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL714134 | 0.79 | RAB9A (0.79) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL714135 | 0.79 | RAB9A (0.79) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL28443608 | 0.78 | RAB9A (0.80) | RAB9ANPC1KDM4ELMNAPKM | |
| Dimethylamine SCHEMBL11573560 | 0.76 | RAB9A (0.86) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL9170782 | 0.75 | RAB9A (0.89) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL9170780 | 0.75 | RAB9A (0.89) | RAB9ANPC1KDM4ELMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706517-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001343-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |