Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | YAP1 | P46937 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368850 | 0.83 | GPR119 (0.50) | GPR119KDM4EPKMYAP1FAAH | |
| SCHEMBL7403646 | 0.82 | GPR119 (0.49) | GPR119KDM4EPKM | |
| SCHEMBL3562965 | 0.81 | GPR119 (0.57) | GPR119KDM4EPKMPOLB | |
| SCHEMBL3249170 | 0.80 | KDM4E (0.61) | GPR119KDM4EPKMYAP1SLC2A1 | |
| SCHEMBL7368405 | 0.79 | GPR119 (0.50) | GPR119KDM4EPKMPOLBCHEK2 | |
| SCHEMBL12813454 | 0.76 | YAP1 (0.66) | GPR119KDM4EPKMYAP1SLC2A1 | |
| SCHEMBL5717213 | 0.75 | KDM4E (0.59) | GPR119KDM4EPKMYAP1 | |
| SCHEMBL6406782 | 0.75 | SLC2A1 (0.58) | GPR119FAAHSLC2A1CHEK2 | |
| SCHEMBL30988946 | 0.74 | KDM4E (0.55) | GPR119KDM4EPKM | |
| SCHEMBL791854 | 0.74 | KDM4E (0.55) | GPR119KDM4EPKMSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064671-A2 | HALOIMIDAZOLE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 AND SEROTONINERGIC 5-HT4 RECEPTORS | SANOFI-SYNTHELABO (FR) | 2001-09-07 | — | — | WO | disclosed |