Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.41 |
| ▸ | DRD3 | P35462 | 7/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8473679 | 0.98 | DRD2 (0.42) | DRD2DRD3ITGB3ITGA2BHTR1A | |
| Hydrochloric Acid SCHEMBL8473847 | 0.87 | SMN1; SMN2 (0.47) | DRD2DRD3HTR1AHTR2AALDH1A1 | |
| SCHEMBL7369000 | 0.87 | SMN1; SMN2 (0.44) | DRD2DRD3HTR1AHTR2AALDH1A1 | |
| SCHEMBL7362005 | 0.86 | ITGB3 (0.52) | DRD2DRD3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8477708 | 0.86 | SMN1; SMN2 (0.46) | DRD2DRD3HTR1AHTR2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8473946 | 0.86 | SMN1; SMN2 (0.46) | DRD2DRD3HTR1AHTR2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7448812 | 0.85 | ITGB3 (0.51) | DRD2DRD3ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7365109 | 0.85 | DRD2 (0.41) | DRD2DRD3ITGB3ITGA2BHTR1A | |
| Hydrochloric Acid SCHEMBL7368304 | 0.74 | ITGB3 (0.54) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7433465 | 0.74 | MAPT (0.44) | DRD2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | claimed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | claimed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | claimed |
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |