Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369205 | 0.93 | PLAU (0.36) | PLAUPLGPLATKDM4CICAM1 | |
| SCHEMBL7369983 | 0.85 | PLAU (0.40) | PLAUPLGPLATKDM4CICAM1 | |
| SCHEMBL7375086 | 0.80 | PLAU (0.44) | PLAUPLGPLAT | |
| SCHEMBL6436546 | 0.80 | PLAU (0.51) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL7364720 | 0.78 | PLAU (0.41) | PLAUPLGPLAT | |
| SCHEMBL6977689 | 0.78 | PLAU (0.36) | PLAUPLGPLATKDM4CICAM1 | |
| SCHEMBL7386231 | 0.77 | PLAU (0.53) | PLAUPLGPLATKDM4C | |
| SCHEMBL7372432 | 0.77 | PLAU (0.54) | PLAUPLGPLAT | |
| SCHEMBL6433371 | 0.77 | PLAU (0.34) | PLAUPLGPLATKDM4CICAM1 | |
| Hydrochloric Acid SCHEMBL7366996 | 0.76 | PLAU (0.42) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |