Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 16/20 | 0.53 |
| ▸ | PLG | P00747 | 6/20 | 0.53 |
| ▸ | PLAT | P00750 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433817 | 0.90 | PLAU (0.44) | PLAUPLGPLATMEN1KMT2A | |
| SCHEMBL6436546 | 0.88 | PLAU (0.51) | PLAUPLGPLATMEN1KMT2A | |
| SCHEMBL6439004 | 0.81 | PLAU (0.46) | PLAUPLGPLATKDM4CNPC1 | |
| SCHEMBL6433372 | 0.80 | PLAU (0.44) | PLAUPLGPLAT | |
| SCHEMBL7369983 | 0.78 | PLAU (0.40) | PLAUPLGPLATMEN1KMT2A | |
| SCHEMBL7369989 | 0.77 | PLAU (0.40) | PLAUPLGPLATKDM4C | |
| Bicarbonate SCHEMBL6977567 | 0.73 | PLAU (0.41) | PLAUPLGPLATMEN1KMT2A | |
| SCHEMBL6433629 | 0.71 | PLAU (0.62) | PLAUPLGPLATKMT2A | |
| Hydrochloric Acid SCHEMBL6433824 | 0.71 | PLAU (0.64) | PLAUPLGPLAT | |
| SCHEMBL6977689 | 0.71 | PLAU (0.36) | PLAUPLGPLATKDM4CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093731-A | Isoquinolines | PFIZER INC. | 2000-07-25 | — | — | US | disclosed |