Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | CTSG | P08311 | 2/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.45 |
| ▸ | CMA1 | P23946 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8827819 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2POLBMAPTPIN1GAA | |
| SCHEMBL9811841 | 0.81 | CA12 (0.67) | SMN1; SMN2PIN1CA12MMP2CA14 | |
| SCHEMBL7375035 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBMAPTPIN1GAA | |
| SCHEMBL14377773 | 0.77 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBPIN1GAARAB9A | |
| SCHEMBL22021302 | 0.77 | MAPT (0.51) | SMN1; SMN2POLBMAPTCA12MMP2 | |
| SCHEMBL11769179 | 0.76 | CYP3A4 (0.42) | SMN1; SMN2POLBMAPTCA12GAA | |
| SCHEMBL8831678 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBMAPTPIN1GAA | |
| SCHEMBL8827769 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBMAPTPIN1ALDH1A1 | |
| SCHEMBL11774080 | 0.73 | CYP3A4 (0.59) | SMN1; SMN2POLBMAPTGAAALDH1A1 | |
| SCHEMBL9857359 | 0.73 | SMN1; SMN2 (0.55) | SMN1; SMN2POLBMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0817778-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030353-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-10-03 | — | — | WO | disclosed |