Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.55 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374031 | 0.84 | MPO (0.47) | NPY5RSMPD3KDM4EALDH1A1HPGD | |
| SCHEMBL27662258 | 0.83 | SMPD3 (0.73) | NPY5RSMPD3KDM4EALDH1A1HPGD | |
| SCHEMBL7374799 | 0.79 | SMPD3 (0.56) | SMPD3KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7374774 | 0.78 | PDE2A (0.57) | NPY5RSMPD3KDM4EALDH1A1HPGD | |
| SCHEMBL29496946 | 0.78 | MEN1 (0.56) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL5797361 | 0.78 | MEN1 (0.56) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL7370877 | 0.77 | MEN1 (0.48) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL31305536 | 0.74 | SMPD3 (0.51) | SMPD3KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL27648497 | 0.74 | L3MBTL1 (0.46) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL26134931 | 0.74 | SMPD3 (0.51) | SMPD3KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |