Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376120 | 0.86 | MAPT (0.47) | CYP11B1CYP11B2NPY5RPDGFRBPDGFRA | |
| SCHEMBL7373890 | 0.86 | PDGFRB (0.44) | CYP11B1CYP11B2NPY5RCYP19A1CYP17A1 | |
| SCHEMBL7365284 | 0.86 | PDGFRB (0.51) | POLBCYP11B1CYP11B2NPY5RPDGFRB | |
| SCHEMBL7371101 | 0.85 | PDGFRB (0.44) | POLBCYP11B1CYP11B2NPY5RCYP19A1 | |
| SCHEMBL10564760 | 0.84 | TUBB4A (0.45) | POLBCYP11B1CYP11B2NPY5RCYP19A1 | |
| SCHEMBL7370473 | 0.84 | PDGFRB (0.42) | CYP11B1CYP11B2NPY5RCYP19A1CYP17A1 | |
| SCHEMBL7367787 | 0.83 | ROS1 (0.48) | KMT2ACYP11B1CYP11B2NPY5RCYP19A1 | |
| Hydrochloric Acid SCHEMBL7369410 | 0.83 | PDE5A (0.58) | MEN1KMT2APOLBCYP11B1CYP11B2 | |
| SCHEMBL27674785 | 0.83 | CYP11B1 (0.48) | CYP11B1CYP11B2NPY5RCYP19A1CYP17A1 | |
| SCHEMBL7365933 | 0.83 | PDGFRB (0.45) | POLBCYP11B1CYP11B2NPY5RCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |