Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROS1 | P08922 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369697 | 0.86 | NPY5R (0.54) | NPY5RCYP11B1CYP11B2CYP19A1CYP2C19 | |
| SCHEMBL7370256 | 0.83 | AMY1A (0.46) | NPY5RCYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL7366319 | 0.83 | NPY5R (0.64) | NPY5RCYP11B1CYP11B2CYP19A1CYP2C19 | |
| SCHEMBL7367947 | 0.83 | NPY5R (0.63) | NPY5RCYP11B1CYP11B2CYP19A1KDM4E | |
| SCHEMBL7375046 | 0.80 | NPY5R (0.55) | NPY5RCYP11B1CYP11B2CYP19A1KDM4E | |
| SCHEMBL7373890 | 0.79 | PDGFRB (0.44) | NPY5RCYP11B1CYP11B2CYP19A1CYP1A2 | |
| SCHEMBL7371101 | 0.78 | PDGFRB (0.44) | NPY5RCYP11B1CYP11B2CYP19A1NPC1 | |
| SCHEMBL7370892 | 0.78 | NPY5R (0.57) | NPY5RCYP11B1CYP11B2CYP19A1CYP2C19 | |
| SCHEMBL28406379 | 0.78 | NPY5R (0.71) | ROS1NPY5RCYP19A1CYP2C19CYP1A2 | |
| SCHEMBL28406383 | 0.77 | CYP19A1 (0.57) | ROS1NPY5RCYP19A1CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |