Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373670 | 0.89 | SMN1; SMN2 (0.43) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL7368631 | 0.89 | MCHR1 (0.44) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL7751032 | 0.86 | HPGD (0.52) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL7743982 | 0.83 | ALDH1A1 (0.64) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL7373541 | 0.81 | ALDH1A1 (0.41) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL7377723 | 0.79 | MEN1 (0.44) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL7371570 | 0.79 | MEN1 (0.46) | HPGDSMN1; SMN2MAPTFABP4KDM4E | |
| SCHEMBL7375488 | 0.77 | MCHR1 (0.47) | ALDH1A1RAB9AL3MBTL1PPARDPPARA | |
| SCHEMBL7369636 | 0.77 | AVPR2 (0.46) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL7377371 | 0.77 | HPGD (0.47) | HPGDALDH1A1SMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |