Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368631 | 0.90 | MCHR1 (0.44) | MCHR1PPARDRAB9AL3MBTL1HDAC1 | |
| SCHEMBL7371273 | 0.90 | MCHR1 (0.46) | MCHR1RAB9AL3MBTL1PLAUOXTR | |
| SCHEMBL7373541 | 0.89 | ALDH1A1 (0.41) | MCHR1PPARDRAB9AL3MBTL1LTB4R | |
| SCHEMBL7373068 | 0.86 | MCHR1 (0.47) | MCHR1RAB9AALDH1A1 | |
| SCHEMBL7373339 | 0.85 | PPARD (0.39) | MCHR1PPARDL3MBTL1LTB4RCNR2 | |
| SCHEMBL7514175 | 0.79 | MCHR1 (0.38) | MCHR1LMNARAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL7377371 | 0.78 | HPGD (0.47) | MCHR1LMNARAB9AALDH1A1 | |
| SCHEMBL7370294 | 0.77 | HPGD (0.49) | MCHR1PPARDRAB9AL3MBTL1LTB4R | |
| SCHEMBL7371612 | 0.76 | L3MBTL1 (0.42) | MCHR1LMNARAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL7373891 | 0.76 | AVPR2 (0.43) | MCHR1LMNARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |