Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370310 | 1.00 | KMT2A (0.58) | KMT2ATDP1PDE4APDE4BPDE4C | |
| SCHEMBL2779361 | 0.84 | KMT2A (0.65) | KMT2ATDP1PDE4APDE4BPDE4C | |
| SCHEMBL7674928 | 0.84 | KMT2A (0.51) | KMT2ATDP1PDE4APDE4BPDE4C | |
| SCHEMBL7674926 | 0.84 | KMT2A (0.51) | KMT2ATDP1PDE4APDE4BPDE4C | |
| SCHEMBL4165132 | 0.80 | RAB9A (0.74) | KMT2ATDP1PDE4APDE4BPDE4C | |
| SCHEMBL29719568 | 0.80 | KMT2A (0.60) | KMT2ATDP1PDE4APDE4BPDE4C | |
| SCHEMBL7674701 | 0.80 | KMT2A (0.64) | KMT2ATDP1PDE4APDE4BPDE4C | |
| SCHEMBL29125555 | 0.80 | KMT2A (0.60) | KMT2ATDP1PDE4APDE4BPDE4C | |
| SCHEMBL7373227 | 0.78 | TDP1 (0.76) | KMT2ATDP1PDE4APDE4BPDE4C | |
| SCHEMBL7373331 | 0.77 | KMT2A (0.57) | KMT2ATDP1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971894-A1 | NICOTINAMIDE DERIVATIVES | Pfizer Products Inc. (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998045268-A1 | NICOTINAMIDE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1998-10-15 | — | — | WO | disclosed |