Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 5/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7369167 | 0.99 | PLAU (0.52) | PLAUALDH1A1HTTKDM4EHSD17B10 | |
| SCHEMBL7365360 | 0.97 | PLAU (0.52) | PLAUALDH1A1HTTKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL7366138 | 0.96 | PLAU (0.51) | PLAUALDH1A1HTTKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL7368606 | 0.96 | PLAU (0.51) | PLAUALDH1A1HTTKDM4EHSD17B10 | |
| SCHEMBL7380961 | 0.91 | PLAU (0.52) | PLAUKDM4EHSD17B10TSHRCCR4 | |
| SCHEMBL7450916 | 0.86 | PLAU (0.50) | PLAUALDH1A1HTTKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL7368464 | 0.85 | PLAU (0.49) | PLAUALDH1A1HTTKDM4EHSD17B10 | |
| SCHEMBL6434558 | 0.85 | CASP3 (0.51) | PLAUTSHRCCR4 | |
| SCHEMBL6435375 | 0.85 | CASP3 (0.51) | PLAUTSHRCCR4 | |
| SCHEMBL6434803 | 0.84 | LMNA (0.44) | PLAUALDH1A1KDM4EHSD17B10CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |
| EP-1077945-A1 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER INC. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000005214-A2 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER INC. (US) | 2000-02-03 | — | — | WO | disclosed |