Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | PARL | Q9H300 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598545 | 0.79 | KDM2B (0.40) | NPSR1CA12CA1CA2CA9 | |
| SCHEMBL27598546 | 0.77 | HTT (0.41) | CYP2C19CYP2C9CYP1A2CYP3A4CA12 | |
| SCHEMBL28079742 | 0.75 | CA12 (0.42) | CYP2C19CYP2C9CYP1A2CA12CA1 | |
| SCHEMBL23248795 | 0.74 | CYP2C9 (0.51) | SLC9A1CYP2C19CYP2C9CYP1A2MMP2 | |
| SCHEMBL4254051 | 0.69 | POLB (0.54) | SLC9A1CYP2C19CYP2C9CYP1A2MMP2 | |
| SCHEMBL30375363 | 0.66 | CA12 (0.50) | SLC9A1CYP2C9CA12CA1CA2 | |
| SCHEMBL5251341 | 0.66 | HDAC3 (0.59) | SLC9A1CYP2C19CYP2C9CYP1A2MEN1 | |
| SCHEMBL2491809 | 0.66 | SLC9A1 (1.00) | SLC9A1CYP2C19NPSR1MEN1KMT2A | |
| SCHEMBL29479875 | 0.66 | SLC9A1 (1.00) | SLC9A1CYP2C19NPSR1MEN1KMT2A | |
| SCHEMBL2958185 | 0.64 | SLC9A1 (0.97) | SLC9A1CYP2C19NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228987-B | Method for preparing pyridazine compound | 住友化学株式会社 | 2017-11-10 | — | — | CN | disclosed |
| EP-1244669-A1 | PYRAZOLOPYRAZINES AND THEIR USE AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001040230-A1 | PYRAZOLOPYRAZINES AND THEIR USE AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-07 | — | — | WO | disclosed |