Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.97 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479875 | 0.98 | SLC9A1 (1.00) | SLC9A1CYP2C19LMNAHPGDHTT | |
| SCHEMBL2491809 | 0.98 | SLC9A1 (1.00) | SLC9A1CYP2C19LMNAHPGDHTT | |
| Ammonia Solution, Strong SCHEMBL3379015 | 0.91 | SLC9A1 (0.85) | SLC9A1CYP2C19LMNAHPGDHTT | |
| SCHEMBL7741924 | 0.85 | CYP2C19 (1.00) | SLC9A1CYP2C19LMNAHPGDHTT | |
| SCHEMBL7746353 | 0.85 | SLC9A1 (1.00) | SLC9A1CYP2C19LMNAHPGDHTT | |
| SCHEMBL4339723 | 0.83 | SLC9A1 (0.72) | SLC9A1CYP2C19LMNAHPGDHTT | |
| SCHEMBL29479890 | 0.83 | SLC9A1 (0.72) | SLC9A1CYP2C19LMNAHPGDHTT | |
| SCHEMBL11439834 | 0.82 | SLC9A1 (0.70) | SLC9A1CYP2C19LMNAHPGDHTT | |
| SCHEMBL7746984 | 0.82 | SLC9A1 (0.72) | SLC9A1CYP2C19LMNAHPGDHTT | |
| SCHEMBL19911490 | 0.80 | SLC9A1 (0.69) | SLC9A1CYP2C19LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759488-B2 | Monoazole ligand platinum analogs | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2010-07-20 | — | — | US | claimed |
| EP-1896491-B1 | MONOAZOLE LIGAND PLATINUM ANALOGS | BIONUMERIK PHARMACEUTICALS INC (US) | 2010-11-17 | — | — | EP | disclosed |
| US-7759488-B2 | Monoazole ligand platinum analogs | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2010-07-20 | — | — | US | disclosed |
| CN-101495459-A | Monoazole ligand platinum analogs | BIONUMERIK PHARMACEUTICALS INC (US) | 2009-07-29 | — | — | CN | disclosed |
| US-20070004696-A1 | cis-aminedichloro [1-(phenylsulfonyl)-1H-benzotriazole] platinum for complexing with DNA and/or RNA | BIONUMERIK PHARMACEUTICALS, INC. | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004696-A1 | cis-aminedichloro [1-(phenylsulfonyl)-1H-benzotriazole] platinum for complexing with DNA and/or RNA | POLRMT, LUC7L2, NSUN3 | SLC9A1 1266/4885CYP2C19 4818/4885LMNA 2631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.