Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5094227 | 0.91 | MET (0.41) | METP2RX4HPGDMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL5093183 | 0.90 | F10 (0.47) | METP2RX4NPC1RAB9AF10 | |
| SCHEMBL5094411 | 0.87 | HSD11B1 (0.44) | HPGDMAPTNPC1RAB9AHSD17B10 | |
| SCHEMBL7160217 | 0.86 | P2RX4 (0.44) | METP2RX4HPGDMAPTNPC1 | |
| SCHEMBL6554470 | 0.85 | SMPD1 (0.43) | HPGDMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL5099764 | 0.85 | MET (0.46) | METP2RX4NPC1RAB9AALDH1A1 | |
| SCHEMBL7123492 | 0.83 | MET (0.36) | METP2RX4HDAC1HDAC2POLB | |
| SCHEMBL5091382 | 0.83 | F10 (0.43) | METHPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL5089072 | 0.82 | HSD17B10 (0.38) | HPGDMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL5089081 | 0.82 | SMN1; SMN2 (0.40) | METHPGDMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206446-A1 | CARBOXYLIC ACID AMIDES, THEIR PRODUCTION AND THEIR USE AS DRUGS | Boehringer Ingelheim Pharma KG (DE) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001010823-A1 | CARBOXYLIC ACID AMIDES, THEIR PRODUCTION AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-02-15 | — | — | WO | disclosed |