Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 5/20 | 0.46 |
| ▸ | FAAH | O00519 | 5/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366403 | 0.95 | NPC1 (0.48) | MAPTNAAAPREPMEN1NPC1 | |
| SCHEMBL7372053 | 0.88 | NPC1 (0.42) | MAPTPREPMEN1NPC1RAB9A | |
| SCHEMBL7374944 | 0.87 | PREP (0.48) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL7372462 | 0.82 | MEN1 (0.50) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL7376617 | 0.82 | TEAD3 (0.41) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10585933 | 0.81 | L3MBTL1 (0.49) | HDAC1HDAC2 | |
| SCHEMBL7373873 | 0.81 | ACE (0.41) | NAAAFAAHPREPLTB4R | |
| SCHEMBL7375339 | 0.80 | HDAC1 (0.43) | MAPTMEN1KMT2AALOX5HDAC1 | |
| SCHEMBL7375341 | 0.80 | HDAC1 (0.43) | MAPTMEN1KMT2AALOX5HDAC1 | |
| SCHEMBL7374067 | 0.80 | HPGD (0.39) | MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461677-B1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | claimed |
| EP-0461677-A1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |