Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370655 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP2C19MEN1KMT2ACA2 | |
| SCHEMBL29434852 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP2C19MEN1KMT2ACA2 | |
| SCHEMBL7348679 | 0.78 | MEN1 (0.64) | CYP1A2CYP2C19MEN1KMT2ACA2 | |
| SCHEMBL7372796 | 0.77 | CYP1A2 (0.62) | CYP1A2CYP2C19MEN1KMT2ACYP2D6 | |
| SCHEMBL13038637 | 0.74 | MEN1 (0.59) | CYP1A2CYP2C19MEN1KMT2AKEAP1 | |
| SCHEMBL2451043 | 0.73 | CYP1A2 (0.57) | CYP1A2CYP2C19MEN1KMT2ACYP2D6 | |
| SCHEMBL1410564 | 0.73 | KEAP1 (0.61) | CYP1A2CYP2C19MEN1KMT2ACYP2D6 | |
| SCHEMBL12648709 | 0.73 | CYP1A2 (0.61) | CYP1A2CYP2C19MEN1KMT2ACA2 | |
| SCHEMBL1411424 | 0.73 | KEAP1 (0.61) | CYP1A2CYP2C19MEN1KMT2ACYP2D6 | |
| SCHEMBL2451041 | 0.73 | CYP1A2 (0.57) | CYP1A2CYP2C19MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997021715-A1 | ALPHA-CYCLOPROPYL-SUBSTITUTED PHENYLGLYCINES AS CNS AGENTS | UNIVERSITY OF BRISTOL (GB) | 1997-06-19 | — | — | WO | disclosed |