Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 13/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371060 | 0.94 | F10 (0.46) | CSNK2A1NR1H4PPARGTRPV1PPARA | |
| SCHEMBL7367697 | 0.87 | NR1H4 (0.45) | NR1H4PPARGPPARDGPBAR1PPARA | |
| SCHEMBL7373717 | 0.86 | NR1H4 (0.57) | NR1H4PPARGPPARDPPARA | |
| SCHEMBL7366476 | 0.85 | HPGD (0.49) | CSNK2A1NR1H4PPARGPPARDGPBAR1 | |
| SCHEMBL7364651 | 0.83 | NR1H4 (0.45) | NR1H4PPARGPPARDGPBAR1PPARA | |
| SCHEMBL6180125 | 0.82 | NR1H4 (0.44) | NR1H4PPARGPPARDGPBAR1TRPV1 | |
| SCHEMBL7365886 | 0.81 | RAB9A (0.47) | CSNK2A1NR1H4PPARGPPARAHPGD | |
| SCHEMBL7369363 | 0.80 | TP53 (0.50) | NR1H4PPARGPPARA | |
| SCHEMBL7371977 | 0.79 | NR1H4 (0.46) | NR1H4PPARGPPARA | |
| SCHEMBL7369592 | 0.79 | NR1H4 (0.50) | NR1H4PPARGPPARDGPBAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |