Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 14/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366501 | 0.94 | F10 (0.47) | NR1H4PPARGPPARDMMP2MMP13 | |
| SCHEMBL7373592 | 0.88 | NR1H4 (0.43) | NR1H4PPARGPPARDGPBAR1PPARA | |
| SCHEMBL6172966 | 0.87 | NR1H4 (0.46) | NR1H4PPARGPPARDGPBAR1PPARA | |
| SCHEMBL7370555 | 0.86 | NR1H4 (0.59) | NR1H4PPARGPPARDPPARA | |
| SCHEMBL7368037 | 0.84 | HPGD (0.51) | NR1H4PPARGPPARDGPBAR1MMP2 | |
| SCHEMBL7372132 | 0.84 | NR1H4 (0.43) | NR1H4PPARGPPARDPPARAMEN1 | |
| SCHEMBL7367092 | 0.83 | NR1H4 (0.46) | NR1H4PPARGPPARDGPBAR1PPARA | |
| SCHEMBL7370668 | 0.82 | CSNK2A1 (0.45) | NR1H4PPARGPPARDGPBAR1PPARA | |
| SCHEMBL6169059 | 0.81 | ESR1 (0.56) | NR1H4PPARGPPARDGPBAR1PPARA | |
| SCHEMBL7367665 | 0.80 | RAB9A (0.48) | NR1H4PPARGPPARAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-06-08 | — | — | EP | disclosed |
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |