Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.55 |
| ▸ | CNR1 | P21554 | 5/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363832 | 0.88 | EPHX2 (0.74) | EPHX2CNR1FAAH | |
| SCHEMBL7371165 | 0.87 | CNR1 (0.62) | EPHX2CNR1CNR2TRPV1 | |
| SCHEMBL7368190 | 0.81 | HDAC1 (0.60) | — | |
| SCHEMBL7368062 | 0.79 | CNR1 (0.59) | EPHX2CNR1CNR2TRPV1 | |
| SCHEMBL7366428 | 0.79 | EPHX2 (0.58) | EPHX2CNR1FAAH | |
| SCHEMBL7368984 | 0.76 | MEN1 (0.76) | EPHX2CNR1CNR2FAAHTRPV1 | |
| SCHEMBL7364362 | 0.75 | LMNA (0.71) | — | |
| SCHEMBL7368390 | 0.74 | HDAC3 (0.56) | EPHX2FAAH | |
| SCHEMBL7371613 | 0.74 | HDAC3 (0.56) | EPHX2FAAH | |
| SCHEMBL7372287 | 0.74 | MEN1 (0.54) | EPHX2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103192-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-08-01 | — | — | US | claimed |
| US-20020177594-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-11-28 | — | — | US | disclosed |
| US-20020103192-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-08-01 | — | — | US | disclosed |
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103192-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC5, HDAC4 | EPHX2 3092/4885CNR1 4370/4885CNR2 4518/4885 |
| US-20020177594-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC11, HDAC3 | EPHX2 3982/4885CNR1 4607/4885CNR2 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.