Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.59 |
| ▸ | CNR2 | P34972 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371165 | 0.82 | CNR1 (0.62) | CNR1CNR2ALDH1A1TRPV1EPHX2 | |
| SCHEMBL7363832 | 0.80 | EPHX2 (0.74) | CNR1ALDH1A1EPHX2 | |
| SCHEMBL7370758 | 0.79 | EPHX2 (0.55) | CNR1CNR2TRPV1EPHX2 | |
| SCHEMBL7370090 | 0.79 | ALDH1A1 (0.63) | ALDH1A1 | |
| SCHEMBL5598110 | 0.75 | PPARG (0.50) | CNR1CNR2ALDH1A1LMNA | |
| SCHEMBL30849698 | 0.74 | MTNR1A (0.69) | CNR1CNR2ALDH1A1 | |
| SCHEMBL7367578 | 0.74 | L3MBTL1 (0.75) | CNR1CNR2ALDH1A1LMNA | |
| SCHEMBL7371566 | 0.72 | HDAC3 (0.76) | ALDH1A1 | |
| SCHEMBL2796059 | 0.72 | HSD17B10 (0.54) | CNR1CNR2ALDH1A1 | |
| SCHEMBL7372978 | 0.72 | HDAC3 (0.57) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103192-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-08-01 | — | — | US | claimed |
| US-20020177594-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-11-28 | — | — | US | disclosed |
| US-20020103192-A1 | Inhibitors of histone deacetylase | ABBOTT LABORATORIES | 2002-08-01 | — | — | US | disclosed |
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103192-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC5, HDAC4 | CNR1 4370/4885CNR2 4518/4885ALDH1A1 546/4885 |
| US-20020177594-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC11, HDAC3 | CNR1 4607/4885CNR2 4785/4885ALDH1A1 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.