Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.63 |
| ▸ | PTPN2 | P17706 | 8/20 | 0.63 |
| ▸ | FBP1 | P09467 | 4/20 | 0.62 |
| ▸ | PTPN5 | P54829 | 8/20 | 0.57 |
| ▸ | HSPD1 | P10809 | 3/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ACLY | P53396 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375039 | 0.91 | PTPN2 (0.56) | PTPN1PTPN2FBP1PTPN5HSPD1 | |
| SCHEMBL7371484 | 0.80 | ACLY (0.53) | FBP1MAPTTP53LMNAACLY | |
| SCHEMBL7367124 | 0.79 | CCR9 (0.51) | PTPN1PTPN2FBP1HSPD1HSPE1 | |
| SCHEMBL7377092 | 0.78 | CCR9 (0.51) | PTPN1PTPN2FBP1HSPD1HSPE1 | |
| SCHEMBL5376836 | 0.75 | PTPN2 (0.69) | PTPN1PTPN2PTPN5HSPD1HSPE1 | |
| SCHEMBL1675376 | 0.75 | SMN1; SMN2 (0.68) | MAPTTP53LMNACASP3SMN1; SMN2 | |
| SCHEMBL5376831 | 0.74 | PTPN2 (0.66) | PTPN1PTPN2PTPN5HSPD1HSPE1 | |
| SCHEMBL4253314 | 0.73 | PTPN1 (0.75) | PTPN1PTPN2PTPN5HSPD1HSPE1 | |
| SCHEMBL30729297 | 0.73 | SMN1; SMN2 (1.00) | PTPN1PTPN2PTPN5MAPTTP53 | |
| SCHEMBL2141073 | 0.73 | SMN1; SMN2 (1.00) | PTPN1PTPN2PTPN5MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074786-A1 | HETEROBIARYLSULPHONAMIDES AND THEIR USE AS PDE 7 INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-10-11 | — | — | WO | claimed |
| WO-2001074786-A1 | HETEROBIARYLSULPHONAMIDES AND THEIR USE AS PDE 7 INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-10-11 | — | — | WO | disclosed |