Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373564 | 0.93 | TOP2A (0.51) | CCR9HPGDALOX15TSHRMAPK1 | |
| SCHEMBL7377092 | 0.86 | CCR9 (0.51) | CCR9HPGDALOX15TSHRMAPK1 | |
| SCHEMBL7369763 | 0.85 | HPGD (0.46) | CCR9HPGDALOX15TSHRMAPK1 | |
| SCHEMBL7370775 | 0.79 | PTPN1 (0.63) | HPGDNPSR1ACLYLMNATP53 | |
| SCHEMBL121768 | 0.78 | IKBKB (0.51) | TSHRLMNATP53MAPTMEN1 | |
| SCHEMBL7375606 | 0.78 | ACLY (0.46) | CCR9HPGDALOX15TSHRMAPK1 | |
| SCHEMBL2957102 | 0.76 | AGPAT2 (0.48) | NPSR1TP53MAPTFBP1ALDH1A1 | |
| SCHEMBL7372057 | 0.75 | KDM4E (0.64) | TSHRACLYLMNAMAPTALDH1A1 | |
| SCHEMBL7375039 | 0.74 | PTPN2 (0.56) | CCR9MAPK1LMNATP53MAPT | |
| SCHEMBL120321 | 0.73 | HTR3A (0.54) | NPSR1LMNAMAPTPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074786-A1 | HETEROBIARYLSULPHONAMIDES AND THEIR USE AS PDE 7 INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-10-11 | — | — | WO | claimed |
| WO-2001074786-A1 | HETEROBIARYLSULPHONAMIDES AND THEIR USE AS PDE 7 INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-10-11 | — | — | WO | disclosed |