SCHEMBL737078

SCHEMBL737078

N#CSc1cnc(N)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14394596 0.75
SCHEMBL9098198 0.75 MYC (0.59)
SCHEMBL702948 0.71
SCHEMBL7212063 0.71
SCHEMBL998733 0.69 MYC (0.51)
SCHEMBL8993668 0.68 MYC (0.51)
SCHEMBL8993621 0.67 MYC (0.50)
SCHEMBL8993653 0.67 MYC (0.50)
SCHEMBL342859 0.67
SCHEMBL10103939 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5491157-A USING 2-AMINO-5-THIAZOLYL THIOCYANATE EASTMAN KODAK COMPANY (US) 1996-02-13 US claimed
EP-0625307-A1 Method and composition for the control of soilborne fungi and prevention of diseases caused by them AMERICAN CYANAMID COMPANY (US) 1994-11-23 EP claimed
JP-7069814-A None JP disclosed
US-20240383884-A1 COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE CORVUS PHARMACEUTICALS, INC. 2024-11-21 US disclosed
US-11897874-B2 Compounds and methods for modulating Interleukin-2-inducible T-cell kinase CORVUS PHARMACEUTICALS, INC. (US) 2024-02-13 US disclosed
US-11897874-B2 Compounds and methods for modulating Interleukin-2-inducible T-cell kinase CORVUS PHARMACEUTICALS, INC. (US) 2024-02-13 US disclosed
CN-117447466-A Oxazole compound and preparation method and application thereof 中国科学院上海药物研究所 2024-01-26 CN disclosed
US-20220363676-A1 COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE CORVUS PHARMACEUTICALS, INC. 2022-11-17 US disclosed
EP-4019515-A1 INHIBITORS OF CYCLIN-DEPENDENT KINASES Dana-Farber Cancer Institute, Inc. (US) 2022-06-29 EP disclosed
EP-4019515-A1 INHIBITORS OF CYCLIN-DEPENDENT KINASES Dana-Farber Cancer Institute, Inc. (US) 2022-06-29 EP disclosed
EP-3534899-B1 COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE CORVUS PHARMACEUTICALS INC (US) 2022-06-01 EP disclosed
US-5491157-A USING 2-AMINO-5-THIAZOLYL THIOCYANATE EASTMAN KODAK COMPANY (US) 1996-02-13 US disclosed
JP-H0769814-A METHOD AND COMPOSITION FOR PREVENTION, CONTROL AND AMELIORATION OF SOILBORNE BACTERIA AND FUNGI AND DISEASE CAUSED THEREBY AMERICAN CYANAMID CO 1995-03-14 JP disclosed
EP-0625307-A1 Method and composition for the control of soilborne fungi and prevention of diseases caused by them AMERICAN CYANAMID COMPANY (US) 1994-11-23 EP disclosed
EP-0625307-A1 Method and composition for the control of soilborne fungi and prevention of diseases caused by them AMERICAN CYANAMID COMPANY (US) 1994-11-23 EP disclosed
US-4156086-A INTERMEDIATES FOR AZO DYES BAYER AKTIENGESELLSCHAFT (DE) 1979-05-22 US disclosed
US-4104268-A POLYACRYLONITRILE, POLYESTERS, POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1978-08-01 US disclosed
US-4038268-A DIAZOTIZATION, COUPLING BAYER AKTIENGESELLSCHAFT (DT) 1977-07-26 US disclosed
US-4006128-A CELLULOSE ACETATES, VINYL POLYMERS, POLYOLEFINS, POLYESTERS BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed
US-4006127-A Cationic diazacyanine dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed