Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | WDR5 | P61964 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | GRK5 | P34947 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993621 | 0.77 | MYC (0.50) | MYCWDR5CCNB2CCNE2CDK1 | |
| SCHEMBL8993668 | 0.75 | MYC (0.51) | MYCWDR5CDK1CDK4CCNE1 | |
| SCHEMBL5215449 | 0.74 | CCNE1 (0.55) | MYCWDR5CDK5CCNB2CCNE2 | |
| SCHEMBL998733 | 0.71 | MYC (0.51) | MYCWDR5CDK5CCNB2CCNE2 | |
| SCHEMBL14394596 | 0.71 | — | — | |
| SCHEMBL12411191 | 0.69 | FDPS (0.58) | MAPK14FDPSLRRK2LIMK1CHEK1 | |
| SCHEMBL2065626 | 0.68 | KDR (0.54) | MYCWDR5LCKKDRNPC1 | |
| SCHEMBL2067788 | 0.68 | KDR (0.63) | MYCWDR5LCKKDRCCNB2 | |
| SCHEMBL14394710 | 0.68 | MYC (0.44) | MYCWDR5CDK5CCNB2CCNE2 | |
| SCHEMBL1133564 | 0.67 | SMN1; SMN2 (0.42) | MYCWDR5CSF1RCDK5CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491157-A | USING 2-AMINO-5-THIAZOLYL THIOCYANATE | EASTMAN KODAK COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| EP-0625307-A1 | Method and composition for the control of soilborne fungi and prevention of diseases caused by them | AMERICAN CYANAMID COMPANY (US) | 1994-11-23 | — | — | EP | disclosed |