SCHEMBL7370795

SCHEMBL7370795

C=CC[C@H](C(=O)NO)[C@@H](CC1CCCC1)C(=O)N[C@H](C(=O)OC1CCCC1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 13/20 0.60
MMP9 P14780 4/20 0.60
ANPEP P15144 3/20 0.60
LTA4H P09960 2/20 0.60
LAP3 P28838 1/20 0.60
NPEPPS P55786 1/20 0.60
ERAP2 Q6P179 1/20 0.60
ERAP1 Q9NZ08 1/20 0.60
MMP3 P08254 11/20 0.41
MMP7 P09237 9/20 0.41
MMP1 P03956 8/20 0.40
MMP8 P22894 2/20 0.40
MMP14 P50281 2/20 0.40
ADAM17 P78536 1/20 0.40
MMP12 P39900 1/20 0.40
MMP13 P45452 1/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6804119 0.89 MMP2 (0.74) MMP2MMP9ANPEPLTA4HLAP3
SCHEMBL6804122 0.89 MMP2 (0.74) MMP2MMP9ANPEPLTA4HLAP3
SCHEMBL6801871 0.89 MMP2 (0.74) MMP2MMP9ANPEPLTA4HLAP3
SCHEMBL6942503 0.79 MMP2 (0.60) MMP2MMP9ANPEPLTA4HLAP3
SCHEMBL7659031 0.79 MMP2 (0.60) MMP2MMP9ANPEPLTA4HLAP3
SCHEMBL7653859 0.77 MMP2 (0.58) MMP2MMP9ANPEPLTA4HLAP3
SCHEMBL6941003 0.77 MMP2 (0.58) MMP2MMP9ANPEPLTA4HLAP3
SCHEMBL6943166 0.75 MMP2 (0.55) MMP2MMP9ANPEPLTA4HLAP3
SCHEMBL7883062 0.75 MMP2 (0.70) MMP2MMP9ANPEPLTA4HLAP3
SCHEMBL7653154 0.75 MMP2 (0.55) MMP2MMP9ANPEPLTA4HLAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6306881-B1 ENZYME INHIBITORS ADMINISTERED TO MAMMALS AS ANTIINFLAMMATORY AGENTS BRITISH BIOTECH PHARMACEUTICALS (GB) 2001-10-23 US disclosed
US-6251940-B1 ADMINISTERING TO THE MAMMAL SUFFERING FROM A DISEASES RESPONSIVE TO INHIBIT MONOCYTE AND/OR MACROPHASE AND/OR LYMPHOCYTE ACTIVATION AND OF LYMPHOCYTE PROLIFERATION AN AMIDE DERIVATIVE BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) 2001-06-26 US disclosed
EP-1063984-A1 INFLAMMATORY CELL INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2001-01-03 EP disclosed
EP-1052986-A1 ANTI-INFLAMMATORY AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2000-11-22 EP disclosed
WO-1999044602-A1 INFLAMMATORY CELL INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1999-09-10 WO disclosed
WO-1999040910-A1 ANTI-INFLAMMATORY AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1999-08-19 WO disclosed