Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 18/20 | 0.60 |
| ▸ | MMP9 | P14780 | 4/20 | 0.60 |
| ▸ | ANPEP | P15144 | 2/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | LAP3 | P28838 | 1/20 | 0.60 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.60 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.60 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.60 |
| ▸ | MMP3 | P08254 | 17/20 | 0.46 |
| ▸ | MMP7 | P09237 | 15/20 | 0.46 |
| ▸ | MMP1 | P03956 | 14/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942503 | 1.00 | MMP2 (0.60) | MMP2MMP9ANPEPLTA4HLAP3 | |
| SCHEMBL6804122 | 0.90 | MMP2 (0.74) | MMP2MMP9ANPEPLTA4HLAP3 | |
| SCHEMBL6804119 | 0.90 | MMP2 (0.74) | MMP2MMP9ANPEPLTA4HLAP3 | |
| SCHEMBL6801871 | 0.90 | MMP2 (0.74) | MMP2MMP9ANPEPLTA4HLAP3 | |
| SCHEMBL7653859 | 0.86 | MMP2 (0.58) | MMP2MMP9ANPEPLTA4HLAP3 | |
| SCHEMBL6941003 | 0.86 | MMP2 (0.58) | MMP2MMP9ANPEPLTA4HLAP3 | |
| SCHEMBL6943166 | 0.82 | MMP2 (0.55) | MMP2MMP9ANPEPLTA4HLAP3 | |
| SCHEMBL7653154 | 0.82 | MMP2 (0.55) | MMP2MMP9ANPEPLTA4HLAP3 | |
| SCHEMBL4420641 | 0.81 | MMP2 (0.51) | MMP2MMP9ANPEPLTA4HLAP3 | |
| SCHEMBL7370795 | 0.79 | MMP2 (0.60) | MMP2MMP9ANPEPLTA4HLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462023-B1 | SUCH AS 2-HYDROXY-HYDROXYCARBAMOYL-METHYL)-4-METHYL-PENTANOYLAMINE)-2-PHENYL -ETHANOIC ACID CYCLOPENTYL ESTER; INHIBITING HYPERPROLIFERATIVE TUMOURGENIC CELLS SUCH AS MELANOMA AND/OR LYMPHOMA CELLS | BRITISH BIOTECH PHARMACEUTICALS, LTD. (GB) | 2002-10-08 | — | — | US | claimed |