Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336962 | 0.92 | MAPT (0.50) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7335541 | 0.91 | KMT2A (0.40) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7345310 | 0.90 | KMT2A (0.44) | KMT2AMEN1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL7373910 | 0.90 | AVPR2 (0.41) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7339794 | 0.88 | GAA (0.47) | KMT2AMEN1SMN1; SMN2RAB9AMLNR | |
| SCHEMBL7341077 | 0.88 | ALDH1A1 (0.54) | KMT2AMEN1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL7378153 | 0.87 | AVPR2 (0.40) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7334640 | 0.84 | MAPT (0.43) | KMT2AMEN1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL7372866 | 0.84 | MAPT (0.42) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7374905 | 0.83 | AVPR2 (0.41) | KMT2AMEN1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |