Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373910 | 0.95 | AVPR2 (0.41) | AVPR2KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL7374776 | 0.92 | L3MBTL1 (0.41) | KMT2ASMN1; SMN2MEN1MAPTPOLB | |
| SCHEMBL7372866 | 0.90 | MAPT (0.42) | AVPR2KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL7374905 | 0.89 | AVPR2 (0.41) | AVPR2KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL7335541 | 0.89 | KMT2A (0.40) | AVPR2KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL7376574 | 0.89 | AVPR2 (0.42) | AVPR2KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL7374760 | 0.88 | AVPR2 (0.43) | AVPR2KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL7378099 | 0.88 | L3MBTL1 (0.43) | KMT2ASMN1; SMN2MEN1MAPTPOLB | |
| SCHEMBL7336962 | 0.87 | MAPT (0.50) | AVPR2KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL7370807 | 0.87 | KMT2A (0.45) | AVPR2KMT2ASMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |