Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.39 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6434236 | 1.00 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1NPC1RAB9AFKBP1A | |
| SCHEMBL6434233 | 1.00 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1NPC1RAB9AFKBP1A | |
| SCHEMBL6434377 | 0.83 | ROCK2 (0.54) | ALDH1A1 | |
| SCHEMBL6434373 | 0.83 | ROCK2 (0.54) | ALDH1A1 | |
| SCHEMBL7507684 | 0.81 | PLAU (0.54) | FKBP1AMEN1KMT2A | |
| SCHEMBL10698916 | 0.76 | L3MBTL1 (0.73) | L3MBTL1ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL10695566 | 0.76 | L3MBTL1 (0.73) | L3MBTL1ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL10699204 | 0.74 | L3MBTL1 (0.69) | L3MBTL1ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7403061 | 0.73 | HPGD (0.43) | L3MBTL1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL9194877 | 0.72 | L3MBTL1 (0.66) | L3MBTL1ALDH1A1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |