Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267260 | 0.90 | FNTA (0.53) | ALDH1A1TDP1L3MBTL1FFAR1 | |
| SCHEMBL7441543 | 0.88 | ALDH1A1 (0.67) | ALDH1A1KEAP1TDP1L3MBTL1FFAR1 | |
| SCHEMBL9315396 | 0.85 | MAPT (0.55) | ALDH1A1L3MBTL1HDAC2HDAC8HDAC6 | |
| SCHEMBL2792481 | 0.83 | CES1 (0.55) | ALDH1A1TDP1L3MBTL1HDAC8HDAC6 | |
| SCHEMBL4222999 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KEAP1TDP1L3MBTL1FFAR1 | |
| SCHEMBL9427256 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KEAP1TDP1L3MBTL1FFAR1 | |
| SCHEMBL3432106 | 0.78 | MEN1 (0.49) | CES2CES1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL16274 | 0.78 | ALDH1A1 (0.67) | ALDH1A1KEAP1TDP1L3MBTL1FFAR1 | |
| SCHEMBL10530175 | 0.78 | ALDH1A1 (0.67) | ALDH1A1KEAP1TDP1L3MBTL1FFAR1 | |
| SCHEMBL9131936 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KEAP1TDP1FFAR1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080595-A1 | Alkanesulfonanilide derivatives and pharmaceutically acceptable acid addition salts thereof | AMERICAN CYANAMID COMPANY (US) | 1983-06-08 | — | — | EP | claimed |
| EP-1218337-A4 | SYNTHESIS OF 3,5,7]-1H-IMIDAZO 1,5-A]IMIDAZOL-2(3H)-ONE COMPOUNDS | TORREY PINES INST (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1218337-A1 | SYNTHESIS OF 3,5,7]-1H-IMIDAZO 1,5-A]IMIDAZOL-2(3H)-ONE COMPOUNDS | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001019783-A1 | SYNTHESIS OF [3,5,7]-1H-IMIDAZO[1,5-A]IMIDAZOL-2(3H)-ONE COMPOUNDS | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2001-03-22 | — | — | WO | disclosed |
| EP-0722436-A4 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | UNIV FLORIDA STATE (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0722436-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5455262-A | Treating arthritis, tumor metastasis, periodontal disease, corneal ulceration, bone resorption diseases, glomerular diseases | FLORIDA STATE UNIVERSITY (US) | 1995-10-03 | — | — | US | disclosed |
| WO-1995009833-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1995-04-13 | — | — | WO | disclosed |